equine herpes virus type 1 (ehv-1) and 4 (ehv-4) infections in horses and donkeys in northeastern turkey
نویسندگان
چکیده
the herpesviruses infections in equides are caused by five different serotypes of viruses, belonging to family herpesviridae. the goal of this study was to conduct a seroepidemiological investigation of equine herpesvirus type 1 (ehv-1) and type 4 (ehv-4) in horses and donkeys raised in two provinces and their villages in northeastern turkey. a total of 666 samples from 423 horses and 243 donkeys that were not immunized against these infections were tested with elisa. while 52.48% of tested horse sera was foundto carry specific antibodies to ehv-1, 83.69% of these serums were found to carry specific antibodies to ehv-4. 51. eighty-five percent of analyzed donkey samples tested positive for ehv-1 and 64.20% of these samples tested positive for ehv-4 antibodies. when the horse and donkey samples were evaluated together, 52.25% were seropositive for ehv-1 and 76.58% were seropositive for ehv-4. this study showed that ehv-1 and ehv-4 infections are quite common in the horses and donkeys being raised in theareas where the study was carried out. in addition, since the area where the study was carried out in the borders of armenia and georgia, the high level of seropositive results for these infections leads to the conclusion that we should consider the risk of diseases spreading to neighboring countries. this is the first study to serologically identify ehv-1 and ehv-4 infections in donkeys raised in turkey.
منابع مشابه
Equine herpes virus type 1 (EHV-1) and 4 (EHV-4) infections in horses and donkeys in northeastern Turkey
The herpesviruses infections in equides are caused by five different serotypes of viruses, belonging to family Herpesviridae. The goal of this study was to conduct a seroepidemiological investigation of equine herpesvirus type 1 (EHV-1) and type 4 (EHV-4) in horses and donkeys raised in two provinces and their villages in northeastern Turkey. A total of 666 samples from 423 horses and 243 donke...
متن کاملEquine herpes virus type 1 (EHV-1) and 4 (EHV-4) infections in horses and donkeys in northeastern Turkey.
The herpesviruses infections in equides are caused by five different serotypes of viruses, belonging to family Herpesviridae. The goal of this study was to conduct a seroepidemiological investigation of equine herpesvirus type 1 (EHV-1) and type 4 (EHV-4) in horses and donkeys raised in two provinces and their villages in northeastern Turkey. A total of 666 samples from 423 horses and 243 donke...
متن کاملPolymorphism of open reading frame 71 of equine herpesvirus-4 (EHV-4) and EHV-1.
Open reading frame (ORF) 71 genes of both equine herpesvirus-1 (EHV-1) and EHV-4 encode a unique glycoprotein, which has been described to vary in molecular mass from 200 to 450 kDa. Using PCR and nucleotide sequence analysis, it was shown that the ORF 71 genes of EHV-1 and EHV-4 are polymorphic due to a variable number of reiterated sequences in two regions, designated regions A and B. Region ...
متن کاملComparative Analysis of Glycoprotein B (gB) of Equine Herpesvirus Type 1 and Type 4 (EHV-1 and EHV-4) in Cellular Tropism and Cell-to-Cell Transmission
Glycoprotein B (gB) plays an important role in alphaherpesvirus cellular entry and acts in concert with gD and the gH/gL complex. To evaluate whether functional differences exist between gB1 and gB4, the corresponding genes were exchanged between the two viruses. The gB4-containing-EHV-1 (EHV-1_gB4) recombinant virus was analyzed for growth in culture, cell tropism, and cell entry rivaling no s...
متن کاملSerological responses and clinical outcome after vaccination of mares and foals with equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) vaccines.
Equine herpesvirus type 1 and type 4 (EHV-1 and EHV-4) cause infections of horses worldwide. While both EHV-1 and EHV-4 cause respiratory disease, abortion and myeloencephalopathy are observed after infection with EHV-1 in the vast majority of cases. Disease control is achieved by hygiene measures that include immunization with either inactivated or modified live virus (MLV) vaccine preparation...
متن کاملThe role of glycoprotein H of equine herpesviruses 1 and 4 (EHV-1 and EHV-4) in cellular host range and integrin binding
Equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) glycoprotein H (gH) has been hypothesized to play a role in direct fusion of the virus envelope with cellular membranes. To investigate gH's role in infection, an EHV-1 mutant lacking gH was created and the gH genes were exchanged between EHV-1 and EHV-4 to determine if gH affects cellular entry and/or host range. In addition, a serine-aspartic ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of veterinary researchناشر: shiraz university
ISSN 1728-1997
دوره 16
شماره 4 2015
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023